Research programme: systemic RNAi therapeutics - Alnylam/Arbutus Biopharma

Drug Profile

Research programme: systemic RNAi therapeutics - Alnylam/Arbutus Biopharma

Alternative Names: TKM-ALDH2

Latest Information Update: 28 Feb 2017

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At a glance

  • Originator Alnylam Pharmaceuticals; Tekmira Pharmaceuticals Corporation
  • Developer Alnylam Pharmaceuticals; Arbutus Biopharma
  • Class RNA
  • Mechanism of Action Aldehyde dehydrogenase 2 inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Alcoholism; Cancer

Most Recent Events

  • 08 Feb 2017 The Supreme Court of British Columbia grants a pre-trial injunction filed against Acuitas Therapeutics by Arbutus Biopharma for Arbutus's lipid nanoparticle (LNP) technology
  • 12 Nov 2012 Alnylam Pharmaceuticals and Tekmira Pharmaceuticals Corporation sign a new licensing agreement regarding RNAi-based therapies, superseding all previous agreements, and resolve all litigation
  • 02 Mar 2012 Preclinical trials in Alcoholism in Canada (Parenteral)
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