Research programme: small molecule SHIP modulators - Aquinox Pharmaceuticals

Drug Profile

Research programme: small molecule SHIP modulators - Aquinox Pharmaceuticals

Alternative Names: AQX-016A; AQX-100; AQX-100 series; AQX-1000 series; AQX-200 series; AQX-252; AQX-273; AQX-278; AQX-300 series; AQX-356; AQX-MN100; AQX-MN106; AQX-MN278; AQX-SHIP inhibitors; AXQ C5; SHIP1 inhibitors

Latest Information Update: 06 Apr 2017

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At a glance

  • Originator Aquinox Pharmaceuticals
  • Class Small molecules
  • Mechanism of Action Inositol-1,4,5-trisphosphate 5 phosphatase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Haematological malignancies; Inflammation
  • Research Haematological disorders; Immunological disorders
  • Discontinued Allergic conjunctivitis; Dry eyes

Most Recent Events

  • 03 Dec 2016 Pharmacodynamics data from a preclinical study in Haematological malignancies presented at the 58th Annual Meeting and Exposition of the American Society of Haematology
  • 04 Jun 2013 Preclinical trials in Haematological malignancies in Canada (unspecified route)
  • 17 Jun 2010 Aquinox completes $US25 million in Series B financing
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