Drug Profile


Alternative Names: Anti-BAFF MAb; Anti-BAFF monoclonal antibody; LY 2127399

Latest Information Update: 20 May 2016

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At a glance

  • Originator Eli Lilly
  • Class Antirheumatics; Monoclonal antibodies
  • Mechanism of Action B cell activating factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Multiple myeloma; Multiple sclerosis; Renal failure; Rheumatoid arthritis; Systemic lupus erythematosus

Most Recent Events

  • 15 Mar 2016 Biomarkers information updated
  • 01 Nov 2015 Eli Lilly terminates phase III trial in Systemic lupus erythematosus in USA, South Korea, Mexico and Puerto Rico due to lack of efficacy (NCT02041091)
  • 01 Aug 2015 Eli Lilly completes a phase I trial in Multiple myeloma (Combination therapy, Second-line therapy or greater) in Japan (IV) (NCT01556438)
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