Sparsentan

Drug Profile

Sparsentan

Alternative Names: DARA - Pharmacopeia; DARA - Retrophin; PS-433540; RE-021

Latest Information Update: 10 Jun 2017

Price : $50

At a glance

  • Originator Bristol-Myers Squibb
  • Developer Retrophin
  • Class Antihypertensives; Isoxazoles; Small molecules; Spiro compounds; Sulfonamides
  • Mechanism of Action Angiotensin type 1 receptor antagonists; Endothelin A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Focal segmental glomerulosclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Focal segmental glomerulosclerosis
  • Discontinued Hypertension

Most Recent Events

  • 01 Jun 2017 Retrophin has patent protection for the use of sparsentan for treating glomerulosclerosis in Europe and USA
  • 01 Mar 2017 Retrophin plans a phase III trial in Focal segmental glomerulosclerosis in USA
  • 13 Sep 2016 Interim adverse events data from a phase II/III trial in focal segmental glomerulosclerosis released by Retrophin
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