Onalespib

Drug Profile

Onalespib

Alternative Names: AT-13387; AT-13387X

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Astex Therapeutics
  • Developer Astex Pharmaceuticals; National Cancer Institute (USA)
  • Class Antineoplastics; Benzamides; Isoindoles; Ketones; Piperazines; Small molecules
  • Mechanism of Action HSP90 heat-shock protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • No development reported Gastrointestinal stromal tumours; Malignant melanoma; Prostate cancer; Solid tumours

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Malignant-melanoma(Combination therapy, Metastatic disease, Second-line therapy or greater) in USA (IV, Infusion)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater) in USA (IV, Infusion)
  • 13 Sep 2016 Phase-II clinical trials in Non-small cell lung cancer (Combination therapy) in France (IV) before September 2016
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