Research programme: antisense glucocorticoid receptor antagonists - Ionis Pharmaceuticals

Drug Profile

Research programme: antisense glucocorticoid receptor antagonists - Ionis Pharmaceuticals

Alternative Names: ISIS-377131

Latest Information Update: 24 Dec 2015

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer Ionis Pharmaceuticals
  • Class Antisense oligonucleotides
  • Mechanism of Action Glucocorticoid receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Type 2 diabetes mellitus

Most Recent Events

  • 18 Dec 2015 Isis Pharmaceuticals is now called Ionis Pharmaceuticals
  • 02 Oct 2007 The agreement between Isis and Ortho-McNeil receives clearance under the Hart-Scott-Rodino Antitrust Improvements Act
  • 17 Sep 2007 Isis and Ortho-McNeil enter into a worldwide collaboration agreement for the discovery, development and commercialisation of antisense drugs for the treatment of metabolic diseases, including ISIS 377131 programme
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