Fremanezumab - Teva Pharmaceutical

Drug Profile

Fremanezumab - Teva Pharmaceutical

Alternative Names: Anti-calcitonin gene-related peptide monoclonal antibody; Anti-CGRP monoclonal antibody; LBR-101; PF-04427429; PF-4427429; RN-307; TEV-48125

Latest Information Update: 27 Nov 2017

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At a glance

  • Originator Rinat Neuroscience
  • Developer Rinat Neuroscience; Teva Pharmaceutical Industries
  • Class Antimigraines; Monoclonal antibodies
  • Mechanism of Action Calcitonin gene-related peptide receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Migraine
  • Phase III Cluster headache

Most Recent Events

  • 27 Nov 2017 Teva plans a phase II trial for Headache (Post-traumatic, prevention) in USA (SC) (NCT03347188)
  • 17 Oct 2017 Preregistration for Migraine (Prevention) in USA (SC)
  • 13 Oct 2017 Teva Branded Pharmaceutical Products, R&D plans the phase III FOCUS trial for Migraine (Prevention) in USA, Belgium, Czechia, Denmark, Finland, France, Germany, Italy, Netherlands, Poland, Spain, Sweden, Switzerland and United Kingdom (SC) (NCT03308968)
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