Drug Profile


Alternative Names: AMG-403; JNJ-42160443

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Amgen
  • Developer Janssen Pharmaceuticals; Janssen Research & Development; Takeda
  • Class Monoclonal antibodies; Non-opioid analgesics; Peptides
  • Mechanism of Action Nerve growth factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Pain
  • Discontinued Back pain; Cancer pain; Musculoskeletal pain; Neuropathic pain

Most Recent Events

  • 24 Jun 2016 Takeda terminates its licence for fulranumab in Japan
  • 31 Mar 2016 Discontinued - Phase-II for Back pain in Belgium, Canada and USA (SC)
  • 31 Mar 2016 Discontinued - Phase-II for Cancer pain (Adjunctive treatment) in USA, Spain, Portugal, Poland and France (SC)
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