Ivacaftor

Drug Profile

Ivacaftor

Alternative Names: Kalydeco; Potentiator VX-770; VX-770

Latest Information Update: 20 Apr 2017

Price : $50

At a glance

  • Originator Cystic Fibrosis Foundation Therapeutics; Vertex Pharmaceuticals
  • Developer Vertex Pharmaceuticals
  • Class Amides; Aminophenols; Quinolones; Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Cystic fibrosis
  • Phase II Chronic obstructive pulmonary disease

Most Recent Events

  • 16 Mar 2017 Phase-II clinical trials in Chronic obstructive pulmonary disease in USA (PO) (NCT03085485)
  • 03 Mar 2017 Vertex Pharmaceuticals plans a phase III trial for Cystic fibrosis (NCT03068312)
  • 23 Feb 2017 Vertex Pharmaceuticals has patent protection for ivacaftor in European Union and USA (Vertex Pharmaceuticals form 10-K, filed in February 2017)
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