Drug Profile


Alternative Names: Anti-complement Factor D antibody; Anti-factor D; Anti-factor D Fab; FCFD4514S; RG7417; TNX-234

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Tanox
  • Developer Genentech
  • Class Eye disorder therapies; Monoclonal antibodies
  • Mechanism of Action Complement factor D inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    Dry age-related macular degeneration
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Dry age-related macular degeneration

Most Recent Events

  • 01 Jul 2016 Roche initiates a phase III extension trial for Dry age-related macular degeneration in USA (NCT02745119)
  • 21 Apr 2016 Roche plans a phase III extension trial for Dry age-related macular degeneration in USA (NCT02745119)
  • 10 Nov 2015 Lampalizumab receives Fast Track designation for Dry age-related macular degeneration [Intravitreous,Injection] in USA
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