Ofranergene obadenovec

Drug Profile

Ofranergene obadenovec

Alternative Names: GT-111; VB 111

Latest Information Update: 14 Mar 2017

Price : $50

At a glance

  • Originator Vascular Biogenics
  • Developer Dana-Farber Cancer Institute; Massachusetts General Hospital; VBL Therapeutics
  • Class Antineoplastics; Gene therapies
  • Mechanism of Action Angiogenesis modulating agents; Gene expression modulators; Vascular disrupting agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioblastoma
  • New Molecular Entity No

Highest Development Phases

  • Phase III Glioblastoma
  • Phase II Ovarian cancer; Thyroid cancer
  • No development reported Lung cancer

Most Recent Events

  • 22 Feb 2017 Updated efficacy data from a phase II trial in Thyroid cancer (Late-stage disease) released by VBL Therapeutics
  • 09 Jan 2017 VBL Therapeutics plans a phase III trial for Ovarian cancer
  • 09 Jan 2017 VBL Therapeutics plans an exploratory clinical trial with a checkpoint inhibitor (Combination therapy)
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