Research programme: proteolytic bacterial enzymes - Hansa Medical

Drug Profile

Research programme: proteolytic bacterial enzymes - Hansa Medical

Alternative Names: Endoglycosidase of Streptococcus pyogenes; EndoS; Second generation IdeS; Second generation Ig-G-degrading enzyme of Streptococcus pyogenes

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Hansa Medical AB
  • Class Anti-inflammatories; Antineoplastics; Bacterial proteins; Enzymes; Immunotherapies
  • Mechanism of Action Immunoglobulin modulators; Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Research Transplant rejection
  • No development reported Autoimmune disorders
  • Discontinued Rheumatoid arthritis; Streptococcal infections

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Autoimmune-disorders in Sweden (Parenteral)
  • 10 Apr 2015 Early research in Transplant rejection (Prevention) in Sweden (Parenteral)
  • 05 Feb 2013 The Swedish Medical Products Agency approves clinical trial application for IdeS in Healthy volunteers
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