Drug Profile


Alternative Names: EMD 281014; LSN2411347; LY-2422347

Latest Information Update: 19 Aug 2014

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At a glance

  • Originator Merck KGaA
  • Developer Eli Lilly; Newron Pharmaceuticals
  • Class Piperazines; Sleep disorder therapies; Small molecules
  • Mechanism of Action Serotonin 2A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported CNS disorders
  • Discontinued Insomnia; Major depressive disorder

Most Recent Events

  • 19 Aug 2014 No development reported - Phase-I for CNS disorders in Italy (PO)
  • 21 Aug 2012 Phase-I clinical trials in CNS disorders in Italy (unspecified route)
  • 05 Apr 2011 Discontinued - Phase-II for Insomnia in USA (unspecified route)
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