Research programme: neurokinin 1 receptor antagonists - Merck and Co.

Drug Profile

Research programme: neurokinin 1 receptor antagonists - Merck and Co.

Alternative Names: Hydroisoindoline tachykinin receptor antagonists - Merck; Hydroisoindoline-based human neurokinin-1 receptor antagonists - Merck; L-760735; Tetrahydroindolizinone NK1 antagonists - Merck

Latest Information Update: 02 Sep 2011

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At a glance

  • Originator Merck & Co
  • Class Isoindoles; Pyrroles
  • Mechanism of Action Neurokinin 1 antagonists; Neurokinin 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • Preclinical Chemotherapy-induced nausea and vomiting
  • No development reported CNS disorders; Major depressive disorder

Most Recent Events

  • 01 Sep 2011 Preclinical development for Chemotherapy induced nausea and vomiting is ongoing in USA
  • 29 Mar 2010 No development reported - Preclinical for CNS disorders in United Kingdom (unspecified route)
  • 29 Mar 2010 No development reported - Preclinical for CNS disorders in USA (unspecified route)
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