MK 0752

Drug Profile

MK 0752

Alternative Names: MK-0752

Latest Information Update: 15 Mar 2016

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At a glance

  • Originator Merck & Co
  • Developer Cancer Research UK; Merck & Co
  • Class Antidementias; Antineoplastics; Propionates; Small molecules; Sulfones
  • Mechanism of Action Amyloid precursor protein secretase inhibitors; Notch signalling pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Breast cancer; CNS cancer; Pancreatic cancer; Solid tumours
  • Discontinued Alzheimer's disease; Haematological malignancies

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 15 Mar 2016 MK 0752 is still in phase I development for Cancer
  • 01 Oct 2014 Cancer Research UK completes a phase I trial in Pancreatic cancer (Combination therapy, Inoperable/Unresectable, Late-stage disease) in United Kingdom (NCT01098344)
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