Drug Profile


Alternative Names: AEGR-733; BMS-201038; Juxtapid; Lojuxta

Latest Information Update: 26 Sep 2017

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Aegerion Pharmaceuticals; Amryt Pharma; Novelion Therapeutics; University of Pennsylvania
  • Class Antihyperlipidaemics; Benzamides; Biphenyl compounds; Fluorenes; Piperidines; Small molecules
  • Mechanism of Action Microsomal triglyceride transfer protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hyperlipoproteinaemia type I; Hyperlipoproteinaemia type IIa
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Hyperlipoproteinaemia type IIa

Most Recent Events

  • 22 Sep 2017 The United States District Court files criminal and civil action against Aegerion Pharmaceuticals forthe introduction of misbranded lomitapide in the US
  • 16 Dec 2016 Launched for Hyperlipoproteinaemia type IIa (Adjunctive treatment) in Japan (PO)
  • 05 Dec 2016 Lomitapide licensed to Amryt Pharma in Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Israel, Italy, Latvia, Lithuania, Luxembourg, Malta, Middle East, Netherlands, North Africa, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, United Kingdom
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