Drug Profile


Alternative Names: Anti-LPA MAbs - Lpath; Lpathomab; mAb against lysophosphatidic acid (LPA) - Lpath

Latest Information Update: 23 Jun 2016

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At a glance

  • Originator Lpath
  • Developer Lpath; University of California at Los Angeles; University of Melbourne
  • Class Monoclonal antibodies
  • Mechanism of Action Lysophosphatidic acid receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Neuropathic pain
  • Preclinical Brain injuries; Fibrosis; Spinal cord injuries
  • Research Diabetic neuropathies
  • No development reported Cancer

Most Recent Events

  • 20 Jun 2016 Lpath receives grant from the US Department of Defense for the preclinical development of Lpathomab™ in Neuropathic pain
  • 19 Apr 2016 Pharmacokinetics and adverse event data from phase I trial in Neuropathic pain (In volunteers) released by Lpath
  • 19 Apr 2016 Lpath completes a phase I trial in Neuropathic pain (In volunteers) in USA (Parenteral) (NCT02341508)
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