R 348

Drug Profile

R 348

Alternative Names: R 932348; R348

Latest Information Update: 28 Feb 2017

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At a glance

  • Originator Rigel Pharmaceuticals
  • Class Antirheumatics; Eye disorder therapies; Skin disorder therapies; Small molecules
  • Mechanism of Action Janus kinase 3 inhibitors; Syk kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Graft-versus-host disease; Keratoconjunctivitis sicca; Psoriasis; Rheumatoid arthritis; Skin disorders; Transplant rejection

Most Recent Events

  • 27 Feb 2017 Discontinued - Phase-II for Graft-versus-host disease in USA (Ophthalmic)
  • 01 Jul 2016 Rigel Pharmaceuticals completes the phase II DROPS-2 trial for Keratoconjunctivitis sicca in patients with ocular Graft-versus-host disease in USA (NCT02040623)
  • 13 Aug 2014 Discontinued - Phase-II for Keratoconjunctivitis sicca in USA (Ophthalmic)
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