Drug Profile


Alternative Names: ACT-128800; Compound 8bo - Actelion; R-3477; RG 3477

Latest Information Update: 24 Feb 2017

Price : $50

At a glance

  • Originator Actelion Pharmaceuticals
  • Class Antipsoriatics; Chlorobenzenes; Imines; Phenyl ethers; Small molecules; Thiazolidines
  • Mechanism of Action Sphingosine 1 phosphate receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Multiple sclerosis
  • Phase II Graft-versus-host disease
  • Phase I Immunological disorders
  • No development reported Plaque psoriasis

Most Recent Events

  • 08 Sep 2016 Phase-III clinical trials in Multiple sclerosis (Adjunctive treatment) in Hungary (PO, Tablet) (EudraCT2012-000541-12)
  • 22 Jun 2015 Phase-II development for Multiple sclerosis completed in Australia, Canada, European Union, Israel, Russia, Switzerland, Ukraine and Serbia
  • 12 May 2015 Phase-III clinical trials in Multiple sclerosis in USA (PO)
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