Research programme: T cell-based therapeutics - Opus Bio

Drug Profile

Research programme: T cell-based therapeutics - Opus Bio

Alternative Names: CAR T-cell based therapies; CAR+ T; Chimeric antigen receptor T cell therapies; LG 690

Latest Information Update: 01 Sep 2014

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At a glance

  • Originator Lentigen Corporation; University of Pennsylvania
  • Developer Medical University of South Carolina; Opus Bio; University of Pennsylvania
  • Class CAR-T cell therapies
  • Mechanism of Action Apoptosis stimulants; Cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Leukaemia; Lymphoma; Malignant melanoma

Most Recent Events

  • 14 Aug 2014 Lentigen Corporation starts operating as Opus Bio and gains certain rights to use lentiviral technology
  • 14 Aug 2014 Miltenyi Biotec acquires the cell and gene therapy assets of Lentigen Corporation, and forms Lentigen Technology
  • 19 Oct 2006 Lentigen Corporation has received an SBIR grant from the National Institutes of Health to evaluate the concept of using lentiviral-engineered T-cells to improve the efficacy of Cancer immunotherapies
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