Omecamtiv mecarbil

Drug Profile

Omecamtiv mecarbil

Alternative Names: AMG-423; CK-1827452; CK-452

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Cytokinetics
  • Developer Amgen; Cytokinetics
  • Class Esters; Heart failure therapies; Organic chemicals; Piperazines; Pyridines; Small molecules
  • Mechanism of Action Cardiac myosin stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Chronic heart failure
  • Phase II Acute heart failure; Heart failure
  • No development reported Angina pectoris; Cardiomyopathies

Most Recent Events

  • 03 Jan 2017 Amgen completes enrollment in a phase II trial in Heart failure in Japan (NCT02695420)
  • 01 Dec 2016 Phase-III clinical trials in Chronic heart failure in USA (PO) (NCT02929329)
  • 14 Nov 2016 Additional efficacy data from the phase II COSMIC-HF trial in Chronic heart failure released by Cytokinetics
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