Drug Profile


Alternative Names: AZ13337019 oxalate; Movantik; Moventig; Naloxegol oxalate; NKTR-118; NKTR-118 oxalate; Oral PEG-naloxol; Pegylated naloxol

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Nektar Therapeutics
  • Developer AstraZeneca; Daiichi Sankyo Company; Knight Therapeutics; Nektar Therapeutics
  • Class Morphinans; Small molecules
  • Mechanism of Action Opioid mu receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Constipation

Most Recent Events

  • 15 Dec 2016 Naloxegol licensed to Knight Therapeutics in Canada and Israel
  • 15 Dec 2016 Preregistration for Constipation in Israel (PO) before 15 December 2016
  • 18 Apr 2016 ProStrakan is now called Kyowa Kirin International
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