Mogamulizumab

Drug Profile

Mogamulizumab

Alternative Names: AMG 761; KW-0761; Poteligeo

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Kyowa Hakko
  • Developer Amgen; Bristol-Myers Squibb; Kyowa Hakko Kirin
  • Class Antiasthmatics; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action CCR4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T cell lymphoma; Adult T-cell leukaemia-lymphoma; Peripheral T-cell lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Adult T-cell leukaemia-lymphoma; Cutaneous T cell lymphoma; Peripheral T-cell lymphoma
  • Phase III Spinal cord disorders
  • Phase I/II Solid tumours
  • Phase I Non-small cell lung cancer
  • Research Mycosis fungoides; Sezary syndrome
  • Discontinued Asthma; Hypersensitivity

Most Recent Events

  • 25 Aug 2017 Early research in Mycosis fungoides and Sezary syndrome in Japan (IV), before August 2017
  • 25 Aug 2017 Mogamulizumab receives Breakthrough Therapy status for Mycosis fungoides (Second-line therapy or greater) in USA
  • 25 Aug 2017 Mogamulizumab receives Breakthrough Therapy status for Sezary syndrome (Second-line therapy or greater) in USA
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