Drug Profile


Alternative Names: GFT-505

Latest Information Update: 16 Feb 2017

Price : $50

At a glance

  • Originator Genfit
  • Class Anti-inflammatories; Antifibrotics; Antihyperglycaemics; Antihyperlipidaemics
  • Mechanism of Action Peroxisome proliferator-activated receptor alpha agonists; Peroxisome proliferator-activated receptor delta agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    Non-alcoholic steatohepatitis
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Non-alcoholic steatohepatitis
  • Preclinical Hepatic fibrosis; Non-alcoholic fatty liver disease; Primary biliary cirrhosis
  • No development reported Lipid metabolism disorders; Type 2 diabetes mellitus

Most Recent Events

  • 08 Feb 2017 The US FDA approves launch of phase II trial for elafibranor in Primary biliary cirrhosis
  • 31 Mar 2016 Preclinical trials in Primary biliary cirrhosis in France (PO)
  • 31 Mar 2016 Genfit plans a clinical trial for Non-alcoholic steatohepatitis (In paediatrics; In patients with liver cirrhosis)
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