Research programme: antibacterials - Achaogen

Drug Profile

Research programme: antibacterials - Achaogen

Alternative Names: Achaogens; ACHN-978; LpxC inhibitors - Achaogen; SOS pathway inhibitors - Achaogen

Latest Information Update: 24 Jun 2016

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At a glance

  • Originator Achaogen
  • Class Antibodies; Immunoglobulin fragments; Monoclonal antibodies; Peptides; Proteins; Small molecules
  • Mechanism of Action LpxC inhibitors; SOS response inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Anthrax; Bacterial infections; Escherichia coli infections; Pseudomonal infections; Yersinia infections

Most Recent Events

  • 15 Mar 2016 Achaogen has patents pending for anti-pseudomonal LpxC inhibitor compounds in USA, Canada, China, Europe, Hong Kong, India, Japan, and Taiwan (Achaogen, Form 10-K, March 2016)
  • 15 Mar 2016 Achaogen announces intention to submit IND to US FDA in 2017
  • 01 Jan 2012 Preclinical trials in Escherichia coli infections in USA (unspecified route)
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