Research programme: BACE1 protein inhibitors - Pfizer

Drug Profile

Research programme: BACE1 protein inhibitors - Pfizer

Alternative Names: WAC-547415; WAY-258131; WY-24454

Latest Information Update: 03 Sep 2010

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At a glance

  • Originator Wyeth
  • Developer Pfizer
  • Class Fluorobenzenes; Hydantoins; Imidazoles; Pyridines; Small molecules
  • Mechanism of Action BACE1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Preclinical Alzheimer's disease

Most Recent Events

  • 26 Aug 2010 Pharmacodynamics data from preclinical trials in Alzheimer's disease presented at the 240th American Chemical Society National Meeting (ACS-2010)
  • 15 Oct 2009 Wyeth has been acquired by Pfizer
  • 20 Aug 2009 Preclinical development is ongoing
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