Drug Profile


Alternative Names: APG-101; Apocept; Asinercept; Asinerceptum; Asunerceptum; CAN-008; CD95-Fc fusion protein; Fas-Fc fusion protein

Latest Information Update: 03 Jan 2017

Price : $50

At a glance

  • Originator Apogenix
  • Developer Apogenix; CANbridge Life Sciences
  • Class Antineoplastics; Immunoglobulin Fc fragments; Recombinant fusion proteins
  • Mechanism of Action Apoptosis inhibitors; Fas ligand protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myelodysplastic syndromes; Glioblastoma; Graft-versus-host disease
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Glioblastoma; Myelodysplastic syndromes

Highest Development Phases

  • Phase II Glioblastoma
  • Phase I Myelodysplastic syndromes
  • Preclinical Solid tumours
  • No development reported Graft-versus-host disease; Myocardial infarction; Stroke

Most Recent Events

  • 05 Dec 2016 Efficacy and adverse events data from a phase I trial in Myelodysplastic syndrome presented at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-Hem-2016)
  • 29 Nov 2016 Pharmacodynamics data from in vitro studies in healthy volunteers presented at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR-2016)
  • 26 Sep 2016 Phase-I/II clinical trials in Glioblastoma (Newly diagnosed, Combination therapy) in Taiwan (IV)
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