Navitoclax

Drug Profile

Navitoclax

Alternative Names: ABT-263; RG 7423; RG 7433

Latest Information Update: 21 Nov 2016

Price : $50

At a glance

  • Originator Abbott Laboratories
  • Developer Abbott Laboratories; AbbVie; Genentech
  • Class Antineoplastics; Benzamides; Morpholines; Piperazines; Small molecules; Sulfones
  • Mechanism of Action Apoptosis stimulants; Proto-oncogene protein c-bcl-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Chronic lymphocytic leukaemia; Lymphoid leukaemia; Lymphoma; Non-small cell lung cancer; Small cell lung cancer; Solid tumours

Most Recent Events

  • 01 Oct 2016 AbbVie completes a phase-I/II clinical trial in Lymphoma in USA and Canada (PO) (NCT00406809)
  • 15 Mar 2016 Biomarkers information updated
  • 01 Feb 2016 Rutgers completes a phase II trial in Prostate cancer (Metastatic disease, Combination therapy, Hormone-refractory) in USA (NCT01828476)
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