Drug Profile


Alternative Names: ASC-08; ITMN-191; ITMN-B; R-7227; RG-7227; RO-5190591

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator Array BioPharma; InterMune
  • Developer Ascletis; Roche
  • Class Antivirals; Carboxylic acids; Cyclopropanes; Isoindoles; Macrocyclic compounds; Pyrrolidines; Small molecules; Sulfonamides
  • Mechanism of Action Hepatitis C protease inhibitors; Hepatitis C virus NS3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Hepatitis C

Most Recent Events

  • 27 Dec 2016 Preregistration for Hepatitis C (Combination therapy, Treatment-naive) in China (PO)
  • 27 Dec 2016 China FDA accepts NDA for danoprevir in Hepatitis C
  • 21 Jun 2016 Interim safety and efficacy data from a phase II EVEREST trial in Chronic hepatitis C released by Ascletis
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