Drug Profile


Alternative Names: AMG 745; PINTA745

Latest Information Update: 11 Apr 2016

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At a glance

  • Originator Amgen
  • Developer Amgen; Atara Biotherapeutics
  • Class Antibodies; Recombinant fusion proteins
  • Mechanism of Action Myostatin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Bone disorders; Muscular atrophy; Nutrition disorders

Most Recent Events

  • 01 Jan 2016 Pinta Biotherapeutics completes a phase I/II trial for Nutritional disorders in USA (NCT01958970)
  • 14 Dec 2015 Discontinued - Phase-I/II for Nutritional disorders in USA (IV)
  • 31 Aug 2015 Atara Biotherapeutics completes enrolment in its phase I/II trial for Nutritional disorders in USA
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