PF 489791

Drug Profile

PF 489791

Alternative Names: PF-00489791; PF-0489791; PF-489791

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Pfizer
  • Class Antihypertensives; Small molecules
  • Mechanism of Action Type 5 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Chronic obstructive pulmonary disease; Diabetic nephropathies; Hypertension; Postherpetic neuralgia; Pulmonary hypertension; Raynaud's disease; Renal failure

Most Recent Events

  • 04 May 2016 Discontinued - Phase-I for Diabetic nephropathies in Belgium (PO) (Pfizer pipeline, May 2016)
  • 04 May 2016 Discontinued - Phase-II for Diabetic nephropathies in Canada, South Korea, United Kingdom, Hong Kong, USA, Mexico, Malaysia, South Africa, Poland, Sweden, Denmark, Slovakia, Australia, India, Serbia (PO) (Pfizer pipeline, May 2016)
  • 17 Jun 2015 Phase-II development for Diabetic nephropathies is ongoing in World
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