AEZS 112

Drug Profile

AEZS 112

Alternative Names: AEZS-112; ZEN-012

Latest Information Update: 22 Mar 2016

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At a glance

  • Originator AEterna Zentaris Inc
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Tubulin polymerisation inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Lymphoma; Solid tumours

Most Recent Events

  • 23 Sep 2009 Final safety and efficacy data from a phase I trial in Solid tumours and lymphoma released by AEterna Zentaris
  • 22 Apr 2009 Interim adverse events, pharmacokinetics and efficacy data from a phase I trial in solid tumours and lymphoma presented at the 100th Annual Meeting of the American Association for Cancer Research (AACR-2009) ,
  • 10 Jan 2007 Phase-I clinical trials in Lymphoma in USA (PO)
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