Rucaparib

Drug Profile

Rucaparib

Alternative Names: AG-014699; AG-14699; CO-338; PF-01367338; PF-1367338; Rubraca; Rucaparib phosphate

Latest Information Update: 12 Oct 2017

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At a glance

  • Originator Cancer Research UK
  • Developer Cancer Research UK; Clovis Oncology; Roche; UNICANCER
  • Class 3-ring heterocyclic compounds; Antineoplastics; Azepines; Indoles; Small molecules
  • Mechanism of Action Poly(ADP-ribose) polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ovarian cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Ovarian cancer
  • Preregistration Fallopian tube cancer; Peritoneal cancer
  • Phase III Prostate cancer
  • Phase II Breast cancer; Pancreatic cancer
  • Phase I Gynaecological cancer; Solid tumours
  • Suspended Malignant melanoma

Most Recent Events

  • 09 Oct 2017 Preregistration for Fallopian tube cancer (Second-line therapy or greater) in USA (PO)
  • 09 Oct 2017 Preregistration for Ovarian cancer (Second-line therapy or greater) in USA (PO)
  • 09 Oct 2017 Preregistration for Peritoneal cancer (Second-line therapy or greater) in USA (PO)
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