SHP 647

Drug Profile

SHP 647

Alternative Names: PF-00547659; PF-547659; SHP647

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Pfizer
  • Class Antiulcers; Monoclonal antibodies
  • Mechanism of Action MADCAM1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Crohn's disease; Ulcerative colitis

Most Recent Events

  • 28 Sep 2017 Shire plans the FIGARO UC 303 phase III trial for Ulcerative colitis (In children, In adolescents, In adults, maintenance therapy) (NCT03290781)
  • 19 Sep 2017 Shire plans the phase III AIDA trial for Ulcerative colitis in January 2018 (NCT03283085)
  • 29 Aug 2017 Shire plans the FIGARO UC 302 phase II trial for Ulcerative colitis (NCT03259308)
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