Nepicastat oral

Drug Profile

Nepicastat oral

Alternative Names: DBH inhibitor programme; DβH inhibitor programme; Nepicastat hydrochloride; SYN-117

Latest Information Update: 02 Mar 2017

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At a glance

  • Originator Roche
  • Developer Biotie Therapies Corp.
  • Class Antiparkinsonians; Anxiolytics; Drug withdrawal therapies; Imidazoles; Neuropsychotherapeutics; Small molecules; Thiones
  • Mechanism of Action Dopamine beta hydroxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Cocaine abuse; Parkinson's disease; Post-traumatic stress disorders

Most Recent Events

  • 27 May 2014 The National Institute on Drug Abuse & Biotie complete enrolment in a phase II trial for Cocaine abuse in USA (NCT01704196)
  • 22 May 2014 Phase-II development is ongoing in USA
  • 13 May 2013 Biotie Therapies initiates enrolment in a phase II trial for Cocaine abuse in USA
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