Bleselumab

Drug Profile

Bleselumab

Alternative Names: 4D11; ASKP 1240

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Kirin Brewery
  • Developer Astellas Pharma; Kyowa Hakko Kirin
  • Class Antipsoriatics; Monoclonal antibodies
  • Mechanism of Action CD40 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Focal segmental glomerulosclerosis; Renal transplant rejection
  • No development reported Transplant rejection
  • Discontinued Plaque psoriasis

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Transplant-rejection(In volunteers) in USA (SC, Injection)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Transplant-rejection(Prevention) in Japan (IV, Infusion)
  • 01 Dec 2016 Phase-II clinical trials in Focal segmental glomerulosclerosis (Prevention of recurrence) in USA (IV) (NCT02921789)
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