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Drug Profile

Verucerfont - GlaxoSmithKline

Alternative Names: 561679; CRF1-antagonist - GSK/Neurocrine; GSK-561679; NBI-77860

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Neurocrine Biosciences
  • Developer GlaxoSmithKline; Neurocrine Biosciences
  • Class Antidepressants; Anxiolytics; Azabicyclo compounds; Oxadiazoles; Pyrazoles; Pyrimidines; Small molecules
  • Mechanism of Action Corticotropin releasing factor receptor 1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Congenital adrenal hyperplasia
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alcoholism; Congenital adrenal hyperplasia; Irritable bowel syndrome; Major depressive disorder; Post-traumatic stress disorders; Social phobia

Most Recent Events

  • 05 Apr 2021 Discontinued - Phase-II for Alcoholism in USA (PO) before April 2021 (Neurocrine Biosciences' pipeline, April 2021) (GlaxoSmithKline's pipeline, April 2021)
  • 05 Apr 2021 Discontinued - Phase-II for Congenital adrenal hyperplasia in USA (PO) before April 2021 (Neurocrine Biosciences' pipeline, April 2021) (GlaxoSmithKline's pipeline, April 2021)
  • 05 Apr 2021 Discontinued - Phase-II for Major depressive disorder in USA (PO) before April 2021 (Neurocrine Biosciences' pipeline, April 2021) (GlaxoSmithKline's pipeline, April 2021)

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