Drug Profile


Alternative Names: Amenalief; ASP-2151; M5220

Latest Information Update: 06 Oct 2017

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At a glance

  • Originator Astellas Pharma
  • Developer Astellas Pharma; Maruho
  • Class Amides; Antivirals; Oxadiazoles; Small molecules
  • Mechanism of Action DNA helicase-primase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Herpes zoster
  • Phase III Herpes simplex virus infections

Most Recent Events

  • 07 Sep 2017 Launched for Herpes zoster in Japan (PO)
  • 03 Jul 2017 Registered for Herpes zoster in Japan (PO)
  • 01 Mar 2016 Mahuro completes a phase III trial in Herpes simplex virus infections in Japan (NCT02209324)
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