EC 0225

Drug Profile

EC 0225

Alternative Names: DAVLBH and mitomycin-C conjugate; Desacetylvinblastine hydrazide and mitomycin-C conjugate; EC0225

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Endocyte
  • Class Antineoplastics; Drug conjugates; Vinca alkaloids
  • Mechanism of Action Alkylating agents; DNA synthesis inhibitors; Microtubule protein inhibitors; Mitosis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for phase-I development in Cancer(Late-stage disease, Metastatic disease) in USA (IV, Injection)
  • 01 Nov 2010 Endocyte completes a phase I trial in metastatic Cancer in USA
  • 04 Jun 2010 Interim adverse events and efficacy data from a phase I trial in Solid tumours presented at the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO-2010)
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