Drug Profile


Alternative Names: Ateroclar Combi; Atozet; Colmibe; Ezetimibe/atorvastatin; Kexrolt; Liptruzet; MK-0653c; Orvatez; SCH-900068; Sersemic; Tioblis; Zardiux; Zoletorv

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Merck/Schering-Plough Pharmaceuticals
  • Developer Merck & Co; Rovi
  • Class Antihyperlipidaemics; Azetidines; Fatty acids; Heptanoic acids; Pyrroles
  • Mechanism of Action Cholesterol absorption inhibitors; HMG-CoA reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Hypercholesterolaemia; Hyperlipidaemia

Most Recent Events

  • 01 Dec 2016 Merck completes a phase III trial for Hypercholesterolaemia in Japan (NCT02460159)
  • 01 May 2016 Merck completes a phase III trial in Hypercholesterolaemia in Japan (NCT02550288)
  • 10 Aug 2015 Launched for Hypercholesterolaemia in United Kingdom, Sweden, Slovenia, Slovakia, Romania, Norway, Malta, Italy, Hungary, Denmark, Czech Republic, Croatia, Bulgaria, Netherlands, Argentina, Ecuador, Colombia, Guatemala, Panama, Peru, El Salvador and Honduras (PO) by August 2015
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