SF 1126

Drug Profile

SF 1126

Alternative Names: PI3K pan inhibitor - SignalRx Pharmaceuticals; SF1126

Latest Information Update: 24 Dec 2016

Price : $50

At a glance

  • Originator Semafore Pharmaceuticals
  • Developer SignalRx Pharmaceuticals
  • Class Antineoplastics; Drug conjugates; Small molecules
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; DNA activated protein kinase inhibitors; MTOR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic lymphocytic leukaemia
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Head and neck cancer
  • Phase I Neuroblastoma
  • Preclinical Hepatocellular carcinoma
  • No development reported Lymphoproliferative disorders; Multiple myeloma; Solid tumours

Most Recent Events

  • 07 Nov 2016 Preclinical trials in Hepatocellular carcinoma in USA (IV)
  • 07 Nov 2016 Parmacodynamics data from preclinical studies in Hepatocellular carcinoma released by SignalRx Pharmaceuticals
  • 01 Nov 2016 Phase-II clinical trials in Head and neck cancer (Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT02644122)
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