Drug Profile


Alternative Names: ACE-031; ActRIIB-IgG1; ActRIIb:Fc Fusion Protein; HGT-4510; RAP-031

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Acceleron Pharma
  • Class Recombinant fusion proteins
  • Mechanism of Action Myostatin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Duchenne muscular dystrophy

Most Recent Events

  • 02 May 2013 Discontinued - Phase-II for Duchenne muscular dystrophy in Canada (SC)
  • 04 Aug 2011 Suspended - Phase-II for Duchenne muscular dystrophy in Canada (SC)
  • 07 Jan 2011 Acceleron Pharma receives grant from the Muscular Dystrophy Association to support clinical trials of ACE 031 in Duchenne muscular dystrophy
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