Drug Profile


Alternative Names: ARRY-520; Filanesib-hydrochloride

Latest Information Update: 17 Oct 2017

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At a glance

  • Originator Array BioPharma
  • Class Amides; Antineoplastics; Fluorobenzenes; Small molecules; Thiadiazoles
  • Mechanism of Action KIF11 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Multiple myeloma
  • No development reported Acute myeloid leukaemia; Myelodysplastic syndromes; Solid tumours

Most Recent Events

  • 05 Sep 2017 Array BioPharma completes the phase II AfFIRM trial in Multiple myeloma (Monotherapy, Second-line therapy or greater) in USA, United Kingdom, Spain, Greece, Germany, France, Canada, Belgium (IV) (NCT02092922)
  • 03 Dec 2016 Safety and efficacy data from a phase Ib/II trial in Multiple myeloma presented at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-2016)
  • 31 May 2016 Array Biopharma completes a phase-II clinical trials for Multiple myeloma (combination therapy, second-line therapy or greater) in USA (IV) (NCT01989325)
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