RPL 554

Drug Profile

RPL 554

Alternative Names: RPL-554

Latest Information Update: 08 Feb 2017

Price : $50

At a glance

  • Originator Vernalis
  • Developer Verona Pharma
  • Class Antiallergics; Antiasthmatics; Imines; Isoquinolines; Small molecules; Urea compounds
  • Mechanism of Action Type 3 cyclic nucleotide phosphodiesterase inhibitors; Type 4 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Allergic rhinitis; Asthma

Highest Development Phases

  • Phase II Allergic asthma; Asthma; Chronic obstructive pulmonary disease
  • Preclinical Cystic fibrosis
  • No development reported Allergic rhinitis

Most Recent Events

  • 18 Jan 2017 Verona Pharma plans a phase II trial for Chronic obstructive pulmonary disease (Adjunctive treatment) in United Kingdom (Inhalation) (NCT03028142)
  • 28 Sep 2016 Preclinical trials in Chronic obstructive pulmonary disease in United Kingdom (Inhalation) before September 2016
  • 28 Sep 2016 Preclinical trials in Cystic fibrosis in United Kingdom (Inhalation) before September 2016
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