RPL 554

Drug Profile

RPL 554

Alternative Names: RPL-554

Latest Information Update: 30 Jun 2017

Price : $50

At a glance

  • Originator Vernalis
  • Developer Verona Pharma
  • Class Antiallergics; Antiasthmatics; Imines; Isoquinolines; Small molecules; Urea compounds
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator stimulants; Type 3 cyclic nucleotide phosphodiesterase inhibitors; Type 4 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Allergic rhinitis; Asthma; Asthma

Highest Development Phases

  • Phase II Asthma; Chronic obstructive pulmonary disease; Cystic fibrosis
  • Discontinued Allergic rhinitis

Most Recent Events

  • 27 Jun 2017 Verona Pharma plans a phase IIb trial for Chronic obstructive pulmonary disease in United Kingdom, Germany, Romania, Bulgaria, and the Czech Republic in the third quarter of 2017
  • 27 Jun 2017 Medicines & Healthcare Products Regulatory Agency (United Kingdom), Federal Institute for Drugs and Medical Devices (BfArM) (Germany), National Agency for Medicines and Medical Devices (Romania), Bulgarian Drug Agency (BDA) and Ministry of Health of the Czech Republic approve IND application for RPL 554 in Chronic obstructive pulmonary disease
  • 05 Jun 2017 Clinical trials in Chronic obstructive pulmonary disease (In volunteers) in USA (Inhalation)
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