Methoxyamine hydrochloride - TRACON

Drug Profile

Methoxyamine hydrochloride - TRACON

Alternative Names: Methoxyamine - TRACON; TRC 102

Latest Information Update: 10 Aug 2017

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At a glance

  • Originator TRACON Pharmaceuticals
  • Developer Case Western Reserve University; National Cancer Institute (USA); TRACON Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action DNA repair inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Glioblastoma; Mesothelioma
  • Phase I/II Solid tumours
  • Phase I Lymphoma; Non-small cell lung cancer

Most Recent Events

  • 15 Jun 2017 Methoxyamine hydrochloride is still in phase I trial for Lymphoma (Combination therapy, Second-line therapy or greater) in USA (PO) and in phase-I development in Solid-tumours (Combination therapy, Late-stage disease) in USA (IV, Infusion) (NCT01851369; NCT00892385)
  • 02 Jun 2017 Adverse events and efficacy data from a phase I trial in Solid tumours presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 18 Apr 2017 National Cancer Institute re-initiates participant recruitment in a phase-I clinical trial in Non-small cell lung cancer (Combination therapy, Late-stage disease) in USA (NCT02535325)
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