Empagliflozin

Drug Profile

Empagliflozin

Alternative Names: BI-10773; Jardiance

Latest Information Update: 05 Oct 2017

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At a glance

  • Originator Boehringer Ingelheim
  • Developer Boehringer Ingelheim; Eli Lilly; Medical University of Vienna; Yale University
  • Class Antihyperglycaemics; Benzhydryl compounds; Cyclic ethers; Glucosides; Small molecules
  • Mechanism of Action Sodium-glucose transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Cardiovascular disorders; Type 2 diabetes mellitus
  • Phase III Type 1 diabetes mellitus
  • Phase II Heart failure; Renal failure

Most Recent Events

  • 12 Sep 2017 Post-hoc analyses efficacy and adverse events data from the phase III EMPA-REG OUTCOME® trial in Type II diabetes released by Boehringer Ingelheim
  • 11 Sep 2017 Pharmacodynamics data from a phase II trial in Type 1 diabetes presented at the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD-2017)
  • 11 Sep 2017 Efficacy data from the phase III EMPA-REG OUTCOME trial in Type II diabetes presented at the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD-2017)
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