Drug Profile


Alternative Names: Anti-CCL2 monoclonal antibody Centocor; Anti-chemokine ligand 2 monoclonal antibody Centocor; Anti-MCP-1 monoclonal antibody Centocor; Anti-monocyte chemoattractant protein 1-monoclonal antibody Centocor; Anti-monocyte chemotactic protein 1 monoclonal antibody Centocor; CNTO-888; Fully human antibody therapeutic for immunology/oncology - Janssen Biotech/MorphoSys

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator MorphoSys
  • Developer Janssen Biotech
  • Class Antifibrotics; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Angiogenesis inhibitors; Chemokine CCL2 inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Idiopathic pulmonary fibrosis; Ovarian cancer; Prostate cancer; Solid tumours

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 20 May 2013 Final efficacy data from a phase II trial in Idiopathic pulmonary fibrosis released by Janssen
  • 09 May 2012 Carlumab is still in phase II development for Idiopathic pulmonary fibrosis
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