Drug Profile


Alternative Names: ALX-0081; ALX-0681; Anti-von Willebrand factor Nanobody - Ablynx; Anti-vWF inhibitor - Ablynx; Anti-vWF nanobody - Ablynx

Latest Information Update: 08 Feb 2017

Price : $50

At a glance

  • Originator Ablynx
  • Class Anticoagulants; Antithrombotics; Proteins
  • Mechanism of Action Von Willebrand factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Thrombotic thrombocytopenic purpura
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preregistration Thrombotic thrombocytopenic purpura
  • Discontinued Thrombosis

Most Recent Events

  • 06 Feb 2017 Preregistration for Thrombotic thrombocytopenic purpura (Adjunctive treatment) in European Union (SC, IV)
  • 29 Sep 2016 Adverse events data from a phase II TITAN trial in Thrombotic thrombocytopenic purpura released by Ablynx
  • 16 Aug 2016 Ablynx initiates enrolment in the (Post-HERCULES) trial for Thrombotic thrombocytopenic purpura in Austria, Hungary and Spain (EudraCT2016-001503-23)
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