Drug Profile


Alternative Names: ADX 48621; Dipraglurant-ER; Dipraglurant-MR

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator Addex Pharmaceuticals
  • Developer Addex Therapeutics
  • Class Alkynes; Heterocyclic bicyclo compounds; Pyridines; Small molecules
  • Mechanism of Action Metabotropic glutamate receptor 5 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Drug-induced dyskinesia
  • New Molecular Entity Yes
  • Available For Licensing Yes - Anxiety disorders; Drug-induced dyskinesia; Dystonia; Major depressive disorder

Highest Development Phases

  • Phase II Drug-induced dyskinesia
  • Phase I Dystonia; Torticollis
  • Preclinical Major depressive disorder
  • Discontinued Anxiety disorders

Most Recent Events

  • 02 Jun 2016 Interim adverse events data from a phase IIa trial in Drug-induced dyskinesia released by Addex Therapeutics
  • 11 Apr 2016 Pharmacodynamics and pharmacokinetics data from a phase I trial in healthy volunteers released by Addex Therapeutics
  • 15 Mar 2016 Adverse events data from a phase I trial in healthy volunteers released by Addex Therapeutics
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