XL 228

Drug Profile

XL 228

Alternative Names: XL-228

Latest Information Update: 09 Mar 2011

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At a glance

  • Originator Exelixis
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Bcr-abl tyrosine kinase inhibitors; Insulin-like growth factor-I receptor antagonists; Src-Family kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Acute lymphoblastic leukaemia; Cancer; Chronic myeloid leukaemia

Most Recent Events

  • 22 Feb 2011 XL 228 is available for collaborations or other external opportunities as of 22 Feb 2011. http://www.exelixis.com/
  • 22 Feb 2011 Discontinued - Phase-I for Acute lymphoblastic leukaemia in USA (IV)
  • 22 Feb 2011 Discontinued - Phase-I for Cancer in USA (IV)
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